The imidazoline receptors and ligands in pain modulation
نویسندگان
چکیده
منابع مشابه
The Role of Parabrachial GABAA Receptors in Pain Modulation in Rats
Background & Objective: The parabrachial nucleus is a critical link in the transmission of short latency nociceptive information to midbrain neurons. GABA(A) receptors have bidirectional roles in controlling nociception and are abundant in the parabrachial region . We examined the effects of bilateral intra parabrachial microinjection of different doses of the GABA(A) receptor agonist, muscimo...
متن کاملThe effects of imidazoline compounds on nociception in animal pain model
The discovery of imidazoline ligands has opened up a new field of study. The investigation of imidazoline actions independent of adrenoceptors started in the mid 1980s. Imidazoline receptors are classified in several subtypes, I1, I2 and I3 binding sites. Although imidazoline sites have been the subjects of research for several years, but there is still controversy about their actions especiall...
متن کاملThe effects of imidazoline compounds on nociception in animal pain model
The discovery of imidazoline ligands has opened up a new field of study. The investigation of imidazoline actions independent of adrenoceptors started in the mid 1980s. Imidazoline receptors are classified in several subtypes, I1, I2 and I3 binding sites. Although imidazoline sites have been the subjects of research for several years, but there is still controversy about their actions especiall...
متن کاملRole of the AMPA receptors of paragigantocellularis lateralis nucleus in the inflammatory pain modulation in male rat
Introduction: The 17β-estradiol acts as a neurosteroid in the brain and modulates nociception by binding to the estrogen receptors and also by allosteric interaction with other membrane-bound receptors like glutamate receptors. Paragigantocellularis lateralis nucleus (LPGi) is one of the important brain regions implicated in the pain modulation. So, this study was designed to evaluate the ...
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ژورنال
عنوان ژورنال: Indian Journal of Pharmacology
سال: 2015
ISSN: 0253-7613
DOI: 10.4103/0253-7613.165196